pañuelo
/paɲuˈelo/ · B1 · noun · m
handkerchief
🤧 paño (cloth) + -uelo (little) = a little cloth
Paño means cloth, from Latin pannus, and -uelo is a Spanish diminutive ending, as in riachuelo, a little river. So a pañuelo is a little cloth: a handkerchief, a neckerchief, or today a paper tissue.