maldición
/maldiˈθjon/ · A2 · noun · f
curse
mal + dición = bad + saying; English malediction is the same word
From Latin maledictio: male (badly) + dicere (to say). A curse is literally a bad-saying. Its opposite is bendición (blessing) = bien + dición, a good-saying. Shouted alone, ¡Maldición! means Curses! or Damn!